The FY2025-1 Small Business Innovation Research Contract (SBIR) Program solicitation has been posted!

 

“The National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC) invite small business concerns (SBCs) to submit research proposals under this Small Business Innovation Research (SBIR) Contract Solicitation. Firms with the capability to conduct research and development (R&D) in any of the health-related topic areas described in Section 12.0, and to commercialize the results of that R&D, are encouraged to participate.”

Please see link above for specific solicitations. Deadline is October 18, 2024

Contract funding is very different from grant funding, and a project needs to be a very (very) good fit to pursue this mechanism. NIAID offers a useful resource to compare differences between grants and contracts – although written specifically for NIAID, these guidelines generally apply across NIH contracts.

Wondering if your company could win non-dilutive funding through an SBIR contract? Have questions about understanding the solicitation details? Reach out today and we will connect you with one of our experts!

  • FY2025 NIH SBIR Contract Topics:

NATIONAL INSTITUTES OF HEALTH (NIH)

NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES (NCATS):

Topic 025        Development of a versatile small footprint benchtop device to perform batch evaporation

Topic 026        Scalable Generation of Liver and Brain Organoids Derived from Human iPS Cells.

 

NATIONAL CANCER INSTITUTE (NCI):

Topic 466        Novel Delivery Systems for RNA-based Cancer Vaccines

Topic 467        Development of Cancer Immunoprevention Agents

Topic 468        Synthetic Microbes (Excluding Oncolytic Viruses) for Immuno-Oncology Therapies

Topic 469        Development of Novel Therapeutics for HPV-related Precancer

Topic 470        Precision Nutrition Interventions to Reduce Cancer-Related Symptoms

Topic 471        Drug-Loaded Carrier Particles for Improved Oral Delivery for Colon Cancer Prevention

Topic 472        Antibody-Drug Conjugates as Radiopharmaceutical Theranostics for Cancer

Topic 473        Point of Care Detection of Antibodies Against HPV16/18 E6 and E7 Oncoproteins in Oropharyngeal Cancer

Topic 474        Point of Care Technologies for GI Cancer Prevention and Early Detection

Topic 475        Development of Digital Biomarkers and Endpoints for Clinical Cancer Care

Topic 476        Digital Twin Software for Optimization of Cancer Radiation Therapy

Topic 477        Wearable Technologies to Facilitate Remote Monitoring of Cancer Patients Following Treatment

Topic 478        Advanced Biomaterials to Improve Cancer Modeling for Research

 

NATIONAL INSTITUTE ON AGING (NIA):

Topic 011        Digital Technologies as Tools to Screen and Monitor Alzheimer’s Disease (AD) and Related Dementias (ADRD)

Topic 012        Modeling Aging through Microphysiological Systems

Topic 013        Leveraging Multimodal and Generative Artificial Intelligence to Advance the Application of Social Robotics in Caregiving

 

NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

Topic 020        Alcohol-activated locking systems for firearms and firearm storage units

Topic 021        Data science tools for accelerating alcohol research

Topic 022        Non-invasive Wearable Alcohol Sensor

 

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID):

Topic 137        New Drug Classes with Novel Mechanisms of Action for HIV, Hepatitis B, and Tuberculosis

Topic 138        Devices and Materials-Based Platforms for the Delivery of Broadly Neutralizing Antibodies

Topic 139        Rapid Diagnostic Assays for Self-Monitoring of Acute or Rebound HIV-1 Infection

Topic 140        Adjuvant Discovery and Down-Selection for Vaccines against Infectious and Immune- Mediated Diseases

Topic 141        Reagents for Immunologic Analysis of Non-mammalian and Underrepresented Mammalian Models

Topic 142        Adjuvant Development for Vaccines and for Autoimmune and Allergic Diseases

Topic 143        Development of Diagnostics for Mycoplasma genitalium Infection

Topic 144        Development of Medical Interventions for Treating Non-Tuberculosis Mycobacterial (NTM) Infections

Topic 145        Diagnostics to Detect Host Immunity to Coccidioidomycosis (Valley fever) or Histoplasmosis

Topic 146        Discovery and Development of Oral Small-molecule Direct-acting Antivirals Targeting Viruses of Pandemic Potential

Topic 147        Software or Web Services to Assess Quality and Reproducibility of Data and Information about Therapeutics and Vaccines

 

NATIONAL INSTITUTE OF MENTAL HEALTH (NIMH):

Topic 001        Point-of-Care and Pharmacy-based Antiretroviral Drug Adherence Assays

Topic 002        Development of novel In-vitro and In-vivo Models to support NeuroHIV Research

 

CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC)

NATIONAL CENTER FOR EMERGING ZOONOTIC AND INFECTIOUS DISEASE (NCEZID):

Topic 032        Canine Vaccines to Prevent Tick Bites

Topic 033        Rapid, Portable, Point-of-Care Carbapenem Resistant Acinetobacter Colonization Screening Diagnostic

Topic 034        Improved Diagnostic Assays for Foodborne and Waterborne Bacterial Pathogens

Topic 035        Improved Diagnostic Assays for Parasitic Diseases

Topic 036        Developing an Over-the-Counter Diagnostic for Valley Fever

Topic 037        Enhancing the CDC Autocidal Gravid Ovitrap to Control Dengue Vectors

 

NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES (NCIRD):

Topic 038        Development of a Molecular Panel to Detect Febrile Rash Illnesses

Topic 039        Synthetic IgM Antibody Controls for Measles, Mumps, and Rubella Assays

 

NATIONAL CENTER FOR INJURY PREVENTION AND CONTROL (NCIPC)

Topic 001        Data Science Solutions to Characterize Polysubstance Use Behavior from Online Sources

 

Are you ready to get started on winning the non-dilutive funding your company needs?

Request a consultation, today!